Paediatric anaesthesia
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Paediatric anaesthesia · Mar 2002
Randomized Controlled Trial Clinical TrialPreoperative oral granisetron for the prevention of vomiting following paediatric surgery.
We evaluated the efficacy of granisetron, 5-hydroxytryptamine type 3 receptor antagonist, given orally, preoperatively, for the prevention of postoperative vomiting in children undergoing general anaesthesia for surgery (inguinal hernia, phimosis-circumcision). ⋯ In summary, preoperative oral granisetron 40 microg x kg(-1) is effective for the prevention of vomiting following paediatric surgery (inguinal hernia, phimosis-circumcision). Increasing the doses to 80 microg x kg(-1) provides no demonstrable additional benefit.
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Paediatric anaesthesia · Mar 2002
Randomized Controlled Trial Clinical TrialIlioinguinal and iliohypogastric nerve block revisited: single shot versus double shot technique for hernia repair in children.
We attempted to determine the efficacy of a one plane ilioinguinal and iliohypogastric nerve block with a single shot and double shot techniques. ⋯ The DS technique, while technically more difficult, does not improve the success rate of the IG-IH nerve block compared with the SS technique.
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Paediatric anaesthesia · Feb 2002
Initial experience with dexmedetomidine in paediatric-aged patients.
We present preliminary clinical experience with the use of dexmedetomidine, an alpha2 adrenergic agonist, in children. Dexmedetomidine was administered in three clinical scenarios: (i) to provide sedation during mechanical ventilation; (ii) intraoperatively for controlled hypotension during an orthopaedic surgical procedure; and (iii) to provide sedation during an invasive procedure. Preliminary data from studies in the adult population, its physiological effects and potential applications in paediatric anaesthesia and critical care are discussed.
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Paediatric anaesthesia · Feb 2002
Randomized Controlled Trial Comparative Study Clinical TrialComparison of rocuronium and suxamethonium for rapid tracheal intubation in children.
The purpose of our study was to determine whether a smaller dose of rocuronium than previously reported could provide similar intubating conditions to suxamethonium during rapid-sequence induction of anaesthesia in children. ⋯ Rocuronium 0.9 mg.kg-1 provides similar intubating conditions to suxamethonium 1.5 mg.kg-1 during modified rapid-sequence induction using alfentanil and thiopentone in children (P=0.671). Rocuronium 0.6 mg.kg-1 was inadequate.