Medicina intensiva
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        Med Intensiva
        
      
  
        
        
      
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    To audit the impact upon mortality of a massive bleeding management protocol (MBP) implemented in our center since 2007. ⋯ These data suggest that the implementation of a goal-directed MBP for prompt and aggressive management of non-trauma, massive bleeding patients is associated to reduced 24-h and 30-day mortality rates.