American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Mar 2000
Amniotic gas values and acid-base status during acute maternal hyperoxemia and hypoxemia in the early fetal sheep.
This study was undertaken to determine amniotic fluid gas values and acid-base balance during maternal hyperoxemia and hypoxemia in early pregnancy. ⋯ Acute maternal hypoxemia during early pregnancy was quickly reflected in amniotic fluid gas values and acid-base balance, whereas hyperoxygenation induced the quickest changes in amniotic fluid PO (2). The metabolic effects of maternal hyperoxemia and hypoxemia were also more pronounced during early pregnancy than at mid pregnancy.