American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Dec 2014
The relationship between a reviewer's recommendation and editorial decision of manuscripts submitted for publication in obstetrics.
We sought to determine the extent to which reviewers' recommendations influence the final editorial disposition of manuscripts submitted for publication. ⋯ The degree of influence on the final disposition of the manuscript depends on the type of recommendation. A recommendation for rejection was the most influential and it was associated with a high rate of rejection. Recommendations for acceptance or minor revisions were also influential but to a lesser degree.
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Am. J. Obstet. Gynecol. · Dec 2014
Treating morning sickness in the United States--changes in prescribing are needed.
Presently, 97.7% of prescriptions for the treatment of nausea and vomiting in pregnancy in the United States are with medications not labeled for use in pregnancy, not indicated for nausea and vomiting in pregnancy, and not classified as safe in pregnancy by the Food and Drug Administration. The use of ondansetron for nausea and vomiting in pregnancy has increased from 50,000 monthly prescriptions in 2008 to 110,000 at the end of 2013, despite unresolved issues regarding fetal safety and Food and Drug Administration warnings about serious dysrhythmias. In April 2013, the Food and Drug Administration approved the combination of doxylamine and pyridoxine, specifically for nausea and vomiting in pregnancy symptoms. Now that a safe and effective drug is available in the United States, there is no reason for women to be exposed to a drug of unproven maternal and fetal safety.
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Am. J. Obstet. Gynecol. · Nov 2014
Effect of umbilical cord milking on morbidity and survival in extremely low gestational age neonates.
Delayed umbilical cord clamping benefits extremely low gestational age neonates (ELGANs) but has not gained wide acceptance. We hypothesized that milking the umbilical cord (MUC) would avoid resuscitation delay but improve hemodynamic stability and reduce rates for composite outcome of severe intraventricular hemorrhage, necrotizing enterocolitis, and/or death before discharge. ⋯ MUC improves early hemodynamic stability and is associated with lower rates of serious morbidity and death among ELGANs.
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Am. J. Obstet. Gynecol. · Nov 2014
Clinical significance of amniotic fluid sludge in twin pregnancies with a short cervical length.
The objective of the study was to determine the clinical significance of amniotic fluid (AF) sludge in twin pregnancies with a short cervix. ⋯ The presence of AF sludge in twin pregnancies with a short cervix is a risk factor for extreme prematurity, histological chorioamnionitis, and perinatal death. Twin A had higher rates of funisitis and neonatal morbidity in the presence of AF sludge.