American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Jun 2007
Risk factors for antepartum and intrapartum stillbirth: a population-based study.
To examine disparities in risk factors for stillbirths and its occurrence in the antepartum versus intrapartum periods. A population-based, cross-sectional study using data on women that delivered singleton births between 20 and 43 weeks in Missouri (1989-1997) was conducted (n = 626,883). Hazard ratios and 95% confidence intervals were derived from regression models and population attributable fractions were estimated to examine the impact of risk factors on stillbirth. ⋯ These risk factors were implicated in 54.9% and 19.7% of antepartum and intrapartum stillbirths, respectively, among African American women, and in a respective 46.6% and 11.9% among white women. Considerable heterogeneity in risk factors between antepartum and intrapartum stillbirths is evident. Knowledge on timing of stillbirth specific risk factors may help clinicians in decreasing antepartum and intrapartum stillbirth risks through monitoring and timely intervention.
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Am. J. Obstet. Gynecol. · May 2007
Use of epidural anesthesia and the risk of acute postpartum urinary retention.
We aimed to examine the relationship between the use of epidural analgesia during labor and acute postpartum urinary retention. ⋯ Epidural analgesia during labor may increase the risk of developing urinary retention by up to 3 times. However, this effect is mediated by other obstetric variables.
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Am. J. Obstet. Gynecol. · Apr 2007
Comparative StudyNatriuretic peptides and hemodynamics in preeclampsia.
The purpose of this study was to evaluate the relationship between natriuretic peptides (NT-proANP and NT-proBNP) and hemodynamic parameters in preeclampsia. ⋯ High NT-proANP and NT-proBNP concentrations in preeclampsia reflect the strain on the heart caused by high afterload, rather than the function of the heart expressed as SI or CI.
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Am. J. Obstet. Gynecol. · Apr 2007
Enhanced synthesis of proinflammatory cytokines by vulvar vestibular fibroblasts: implications for vulvar vestibulitis.
The objective of the study was to determine whether vestibular fibroblasts from vulvar vestibulitis (VVS) patients produce higher proinflammatory cytokine levels when provoked with Candida albicans (yeast) and alpha-melanocyte-stimulating hormone (alpha-MSH) in vitro. ⋯ Localized pain of VVS may results from regionally elevated cytokines produced by vulvar vestibule-specific fibroblasts.