American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Apr 2005
The interleukin-6--174 single nucleotide polymorphism: cervical protein production and the risk of preterm delivery.
The purpose of this study was to determine the associations between preterm delivery (PTD), cervical fluid interleukin-6 (IL-6) concentration, and the single nucleotide polymorphism at position -174 in the IL-6 gene. ⋯ Cervical fluid concentrations of IL-6 were not elevated in symptomatic women destined to have a spontaneous PTD. The presence of maternal IL-6 -174C was not associated with cervical fluid concentration of IL-6 or risk of PTD.
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Am. J. Obstet. Gynecol. · Apr 2005
Multicenter Study Comparative StudyAssessment of resident surgical skills: is testing feasible?
We have previously shown that in a single residency program objective structured assessment of technical skills (OSATS) is a reliable and valid method of assessing surgical competency. Our goal was to establish feasibility of this evaluation instrument when administered at multiple residency programs throughout the US, and assess the impact of a laboratory-based surgical curriculum on results. ⋯ Large-scale testing has confirmed that OSATS is an objective, reliable, and valid method to assess surgical skills, and can easily be administered in most residency programs. A laboratory-based surgical curriculum improved test results and reduced time to complete tasks.
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Am. J. Obstet. Gynecol. · Apr 2005
Comparative StudyObstetric outcomes in women with two prior cesarean deliveries: is vaginal birth after cesarean delivery a viable option?
This study was undertaken to compare clinical outcomes in women with 1 versus 2 prior cesarean deliveries who attempt vaginal birth after cesarean delivery (VBAC) and also to compare clinical outcomes of women with 2 prior cesarean deliveries who attempt VBAC or opt for a repeat cesarean delivery. ⋯ The likelihood of major complications is higher with a VBAC attempt in women with 2 prior cesarean deliveries compared with those with a single prior cesarean delivery. In women with 2 prior cesarean deliveries, while major complications are increased in those who attempt VBAC relative to elective repeat cesarean delivery, the absolute risk of major complications remains low.
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Am. J. Obstet. Gynecol. · Apr 2005
Comparative StudyExperimental intrauterine Ureaplasma infection in sheep.
Prenatal Ureaplasma spp exposure is associated with preterm birth and modulates the neonates' susceptibility to respiratory distress syndrome and bronchopulmonary dysplasia. We hypothesized that intra-amniotic ureaplasmas would cause lung inflammation and alter fetal lung development. ⋯ Long-term exposure to ureaplasmas in amniotic fluid alters ovine fetal development.
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Am. J. Obstet. Gynecol. · Mar 2005
Randomized Controlled Trial Clinical TrialFactors predicting severe perineal trauma during childbirth: role of forceps delivery routinely combined with mediolateral episiotomy.
Anal sphincter injury and its sequelae are a recognized complication of vaginal childbirth. The aim of the present study was to identify risk factors for third- and fourth-degree perineal tears in patients undergoing either spontaneous or vaginal-assisted delivery by forceps routinely combined with mediolateral episiotomy. ⋯ In consistence with previous reports, women who are vaginally delivered of a large infant are at a high risk for sphincter damage. Although the rate of these complications was surprisingly low in vaginally assisted childbirth, the use of forceps, even if routinely combined with mediolateral episiotomy, should be minimized whenever possible.