American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Jun 1975
Erythrocytosis due to erythropoietin-producing uterine fibromyoma.
Erythrocytosis has been observed to occur infrequently in association with uterine fibromyomas. Study of this case revealed erythrocytosis prior to surgery and a remission was noted after myomectomy. ⋯ We postulate that the tumor itself was responsible for the erythrocytosis observed. The mechanisms proposed to explain polycythemia in such a tumor were revised and our conclusion is that the tumor produced the erythropoietin autonomously and is not subjected to feedback control mechanism.
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Am. J. Obstet. Gynecol. · Apr 1975
Effect of regional analgesia on maternal oxygen consumption during the first stage of labor.
Oxygen consumption, tidal volume, and minute volume decreased in 20 patients during the first stage of labor after either epidural or paracervical block. The elimination of pain with optimum regional analgesia is associated with a decrease in tidal and minute volumes, apprehension, and consequently a decreased oxygen consumption. These factors may contribute to a decrease in maternal lactic acidosis during labor.
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Am. J. Obstet. Gynecol. · Feb 1975
The acid-base and biochemical characteristics of intrapartum fetal asphyxia.
The maternal and fetal acid-base, lactate, and pyruvate characteristics during the course of labor and at delivery were studied in 124 patients delivered of an infant with evidence of metabolic acidosis at delivery. This metabolic acidosis is principally caused by hyperlactatemia resulting from the tissue oxygen debt accompanying fetal asphyxia. ⋯ This evidence of fetal asphyxia developed during the last half and principally during the last two hours of the intrapartum period. Acid-base assessment of fetal blood with identification of a metabolic acidosis will provide an accurate objective diagnosis of intrapartum fetal asphyxia.
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Am. J. Obstet. Gynecol. · Feb 1975
Clinical characteristics of pregnancies complicated by intrapartum fetal asphyxia.
The clinical characteristics of 124 pregnancies complicated by intrapartum fetal asphyxia have been reviewed. The evidence of fetal asphyxia tends to appear earlier in patients with maternal medical and obstetric complications than in those with labor complications. ⋯ Low Apgar scores occurred in 40 per cent of infants with moderate asphyxia and in 80 per cent of infants with severe asphyxia at delivery. In the newborn infants, clinical evidence of cerebral abnormality was observed in 3 per cent, and evidence of the respiratory distress syndrome was seen in 3 per cent of the study group.