Neuroimaging clinics of North America
-
Neuroimaging Clin. N. Am. · Feb 1995
ReviewSingle photon emission computed tomography in Alzheimer's disease and related disorders.
Alzheimer's disease and other dementia syndromes can be characterized by single photon emission computed tomography (SPECT). SPECT can be used to measure cerebral blood flow or neurotransmitter activity in these disorders. SPECT can help distinguish various neurologic disorders and also help elucidate their pathophysiologic processes. This article focuses on the use of SPECT in the study of Alzheimer's disease and related neurologic disorders.
-
Magnetic resonance imaging is a useful process in the evaluation and follow-up examination of intracranial vascular malformations. Magnetic resonance imaging as related to the four subtypes of these malformations, arteriovenous malformations, venous angiomas, cavernous malformations, and capillary telangiectasis, is discussed.
-
Neuroimaging Clin. N. Am. · Feb 1994
ReviewImproved detection of gadolinium enhancement using magnetization transfer imaging.
Magnetization transfer (MT) imaging is a new MR imaging technique in which off-resonance radiofrequency pulses are used to selectively saturate protons in macromolecules. This saturation effect is transferred subsequently (by dipolar and chemical exchange interactions) to protons in free water, thereby altering tissue relaxation times and modulating image contrast. Gadolinium enhancement is not significantly mediated by macromolecular interactions and is, therefore, not suppressed by MT pulses. The theory underlying the use of the MT technique is presented, with examples of its clinical usefulness in improving contrast enhancement for a variety of central nervous system diseases.