American journal of critical care : an official publication, American Association of Critical-Care Nurses
-
Elevated perioperative heart rate potentially causes perioperative myocardial injury because of imbalance in oxygen supply and demand. However, large multicenter studies evaluating early postoperative heart rate and major adverse cardiac and cerebrovascular events (MACCEs) are lacking. ⋯ More research is needed to assess the usefulness of heart rate measurement in patients after CABG.
-
Meta Analysis
Prevention of Endotracheal Tube-Related Pressure Injury: A Systematic Review and Meta-analysis.
Hospital-acquired pressure injuries, including those related to airway devices, are a significant source of morbidity in critically ill patients. ⋯ Airway device-related pressure injuries are common in critically ill patients, and patients with nasotracheal tubes are particularly susceptible to iatrogenic harm. Fastening devices and barrier dressings decrease the incidence of injury. Evidence regarding interventions is limited by lack of standardized assessments.
-
Intensive care unit (ICU) delirium is associated with a proinflammatory state and poor outcomes. An epigenetic mechanism may modify inflammation. ⋯ Temporal variability in inflammatory gene methylation occurs after ICU admission. Delirium, female sex, and older age were more common with higher IL6ST methylation that decreased over time. Larger studies are needed to further elucidate these relationships.