International archives of allergy and immunology
-
Int. Arch. Allergy Immunol. · Jan 2016
Observational StudyBlood Coagulation and Asthma Exacerbation in Children.
Recent studies have demonstrated the activation of coagulation pathways in asthmatic airways. This study aimed to determine systemic blood coagulation during asthma exacerbation compared with the stable state in children. ⋯ Evidence was found of increased endothelial activation and increased PAI-1 during asthma exacerbation. This may emphasize the potential role of blood coagulation in asthma exacerbation.