The American journal of the medical sciences
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Review Case Reports
Spontaneous resolution of a cyst of the septum pellucidum.
Septum pellucidum cysts are rare clinical findings. Although their optimal treatment remains controversial, large cysts causing hydrocephalus or neural compression should be treated surgically. However, spontaneous resolution can also occur. ⋯ To the best of the authors' knowledge, this is only the third reported case of spontaneous resolution of a septum pellucidum cyst. This case suggests that a symptomatic septum pellucidum cyst is not an absolute indication for surgical treatment. A conservative approach with close follow-up with computerized tomography or magnetic resonance imaging is strongly recommended unless the cyst causes obvious hydrocephalus or progressive neurological deterioration.
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Major depressive disorder (MDD) is a common psychiatric illness affecting nearly 20% of adults in the United States at least once during their lifetime. MDD is frequently diagnosed and treated in the primary care setting. ⋯ This article presents an overview of diagnostic and treatment guidelines for MDD and focuses on challenges encountered by primary care physicians. The role of antidepressant medications, psychotherapy and nonpharmacologic interventions for the treatment of patients with MDD is described, and factors influencing treatment selection, such as adverse event profiles and patient characteristics, are examined.
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Review Historical Article
From laboratory to bedside: ethical, legal and social issues in translational research.