The American journal of the medical sciences
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Gastric cancer is one of the most aggressive tumors, usually resulting in metastasis, and therapies for advanced gastric cancer remain limited. Drug resistance is the main reason for chemotherapeutic failure in gastric cancer. Wiskott-Aldrich syndrome protein family member 3 (WASF3) is required for invasion and metastasis of different cancers. However, there has been little study of WASF3 expression involvement in gastric cancer. In this study, we explored the role of WASF3 in the sensitivity of gastric cancer to oxaliplatin, and the underlying mechanisms. ⋯ Our analysis demonstrates WASF3 targeting is a new potential therapeutic strategy for gastric cancer.
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Acute myocardial infarction (AMI) carries a substantial mortality and morbidity burden. The purpose of this study is to provide annual mean cost per patient and national level estimates of direct and indirect costs (lost productivity from morbidity and premature mortality) associated with AMI. ⋯ The study finds that the economic burden of AMI is substantial, for which effective prevention could result in significant health and productivity cost savings.
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Letter Case Reports
Posterior Mediastinal Mature Cystic Teratoma-Known But Rare Entity.