Osteoarthritis and cartilage
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Osteoarthr. Cartil. · Mar 2004
Multicenter Study Comparative StudyRelative efficiency and validity properties of a visual analogue vs a categorical scaled version of the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) Index: Spanish versions.
To compare the performance of visual analogue (VAS) vs categorical (CT) scaled versions of the three subscales (pain, stiffness and difficulty) of the WOMAC Index in patients with knee osteoarthritis. ⋯ We have shown that both the VAS version of WOMAC have adequate evaluative and discriminative properties. We found the pain and physical function scales in VAS format and the stiffness scale in CT format to have a slightly better performance in this sample.
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Osteoarthr. Cartil. · Nov 2003
Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis.
To describe an in vivo model in the rat in which change in weight distribution is used as a measure of disease progression and efficacy of acetaminophen and two nonsteroidal anti-inflammatory drugs (NSAIDs) in a model of monosodium iodoacetate (MIA)-induced osteoarthritis (OA). ⋯ The determination of differences in hind paw weight distribution in the rat MIA model of OA is a technically straightforward, reproducible method that is predictive of the effects of anti-inflammatory and analgesic agents. This system may be useful for the discovery of novel pharmacologic agents in human OA.
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Osteoarthr. Cartil. · Aug 2003
Reliability and validity of the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index in Italian patients with osteoarthritis of the knee.
The Western Ontario and McMaster Universities (WOMAC) Osteoarthritis (OA) Index is a tested questionnaire to assess symptoms and physical functional disability in patients with OA of the knee and the hip. We adapted the WOMAC for the Italian language and tested its metric properties in 304 patients with symptomatic OA of the knee. ⋯ The Italian version of WOMAC is a reliable and valid instrument for evaluating the severity of OA of the knee, with metric properties in agreement with the original, widely used version.
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Osteoarthr. Cartil. · Jul 2003
Linking osteoarthritis-specific health-status measures to the International Classification of Functioning, Disability, and Health (ICF).
The objective of this study was to link the Western Ontario and McMaster Universities (WOMAC) and Lequesne-Algofunctional indices to the ICF on the basis of linking rules developed specifically to accomplish this aim. The linking process enables the understanding of the relationship between health-status measures and the ICF. ⋯ The results of the linking process reflect both the structure of the two questionnaires studied and the relationship between them, showing that the ICF classification can become the cardinal reference for existing health-status measures.