Anaesthesia
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Twenty patients undergoing microlaryngoscopy were anaesthetised with thiopentone and nitrous oxide. Half of the patients received 1.0-1.5 mg of fentanyl during anaesthesia, the effect of which was antagonised by naloxone 0.4 mg intravenously and 0.4 mg subcutaneously. The other patients served as controls and received saline instead of fentanyl and naloxone. ⋯ However, there were no significant differences between patients given fentanyl with naloxone, and those given saline, in respect of arterial pressure, heart rate or dysrhythmia during recovery. No patient vomited, or appeared nauseated when observed afterwards in the operating room. One patient vomited several hours after naloxone.
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Comparative Study
Isobaric bupivacaine and hyperbaric amethocaine for spinal analgesia. A clinical comparison.
A 15 mg dose of isobaric bupivacaine 0.5% solution for spinal analgesia was compared with a clinically indicated dose of hyperbaric amethocaine 1% solution (10-16 mg) in 123 patients undergoing orthopaedic, urological and general surgical procedures. The 63 patients who received bupivacaine had a more limited spread of analgesia, which lasted longer and was accompanied by less hypotension and fewer complications than those who received amethocaine.