Der Anaesthesist
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Anaesthesist
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Randomized Controlled Trial
Effect of low tidal volume with PEEP on respiratory function in infants undergoing one-lung ventilation.
An increasing number of studies have shown that low tidal volume (TV) with positive end-expiratory pressure (PEEP) offers lung protection during one-lung ventilation (OLV). Considering the unique physiological characteristics of infants, we aimed to determine the feasibility and effect of low TV with PEEP in infants undergoing OLV during thoracoscopy. ⋯ Low TV with PEEP could be an effective intraoperative ventilation strategy for infants undergoing OLV during video-assisted thoracoscopic surgery and may reduce the risk of lung injury. However, this strategy, as well as the influence of intraoperative hypercapnia on infants, needs further investigation.
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Editorial Comment
[The central nervous system as the target organ of general anesthesia].