Der Anaesthesist
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Adaequate antibiotic therapy is crucial for successful anti-infective therapy. In addition to the choice of the right antibiotic and the duration of therapy, the dose also plays a decisive role. ⋯ Since pharmacokinetic differences between plasma and the interstitial fluid of different target tissues have been observed for different antibiotics, the measurement is also necessary in the target tissue. The technique of microdialysis is best suited for this purpose as it allows concentrations to be measured continuously in the target tissue.
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The application of artificial intelligence (AI) is currently changing very different areas of life. Artificial intelligence involves the emulation of human behavior with the aid of methods from mathematics and informatics. ⋯ Although the majority of the applications in medicine are still limited to data analysis and research, it is certain that ML will become increasingly more important in scientific and clinical aspects in this supportive function. Therefore, it is necessary for clinicians to have at least a basic understanding of the functional principles, strengths and weaknesses of ML.
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Review Case Reports
["Legal highs" (new psychoactive substances) : What does the anesthesiologist need to know?]
In recent years, the social media, the press and the internet have reported more about the topic of "legal highs" and new psychoactive substances (NPS). The use of these drugs is accompanied by a serious risk of undesired side effects, intoxication and even death. The often unknown chemical composition, unspecific clinical presentations and lack of quickly available routine diagnostic tests are aggravating factors in this situation. For anesthesiologists, knowledge of this dangerous substance class plays an important role in the field of preclinical treatment, perioperative management and intensive medical care.
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Multicenter Study
[Implementation of anesthesia quality indicators in Germany : A prospective, national, multicenter quality improvement study].
In 2016 the German Society of Anesthesiology and Intensive Care Medicine (DGAI) and the Association of German Anesthetists (BDA) published 10 quality indicators (QI) to compare and improve the quality of anesthesia care in Germany. So far, there is no evidence for the feasibility of implementation of these QI in hospitals. ⋯ In this study the implementation of QI was proven to be mostly feasible in the participating German hospitals. Although several QI could be implemented with minor effort, more time, financial and structural resources would be required for some QI, such as the QI postoperative visit.