Der Anaesthesist
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Complications associated with local infiltration of ornithine-8-vasopressin (O-8-V) during general anesthesia (GA) are documented. Severe and extremely severe complications range around 20%; fatalities have been reported. The incidence of complications is associated with age, pre-existing cardiovascular or pulmorespiratory disease, and dosage administered. ⋯ For data analysis, patients were allocated to 4 groups according to the dosage of O-8-V administered. Systolic and diastolic pressures increased to above control in all groups; however, no inter-group differences were found for blood pressure or heart rate. It is concluded that the risks associated with local infiltration of soft tissues with O-8-V during GA can be attenuated by a protocol such as the one established for this prospective study.(ABSTRACT TRUNCATED AT 250 WORDS)
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Randomized Controlled Trial Comparative Study Clinical Trial
[Does directed bronchoscopic bronchial cleansing have an advantage over conventional suctioning? A prospective study of hemodynamics, gas exchange and suction-induced mucosal lesions in long-term ventilated patients].
Hypoxic complications and epithelial damage to the trachea and bronchi during conventional blind suctioning have been described in the literature. Fiberoptic suctioning and examination of the trachea of each long-term ventilator patient as a routine method has been recommended in recent studies. We investigated the effect of a conventional tracheal suction technique compared to precise fiberbronchoscopic suction on cardiocirculatory function and gas exchange in mechanically ventilated patients. ⋯ There was no effect on cardiocirculatory function in either group (Figs. 1 and 2), but we found a decrease in arterial PO2 after suctioning in all patients (group I from 99 +/- 25 to 81 +/- 19 mmHg, group II from 104 +/- 23 to 80 +/- 17 mmHg [Fig. 3]). The time needed to re-establish the initial PaO2 after suctioning was significantly different in both groups. Whereas the PaO2 returned to the initial value within 2 min after conventional suctioning, we found a decrease in PaO2 in the bronchoscopic group even after 15 min.(ABSTRACT TRUNCATED AT 250 WORDS)
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Randomized Controlled Trial Comparative Study Clinical Trial
[Effect of different pre-oxygenation procedures on arterial oxygen status].
There are different opinions regarding efficiency, duration, and techniques of preoxygenation. It was the aim of our study to systematically investigate the effectiveness of different preoxygenation methods by means of arterial blood gas parameters (paO2, SaO2, and CaO2). METHODS. ⋯ Most important was the manner of holding the face mask. With a tightly fitting mask, preoxygenation was more effective than with the face mask one digit away from mouth and nose, independent of preoxygenation time and oxygen flow (Table 3). The SaO2 (Fig. 2) increased in the same manner with the different preoxygenation techniques from 94.0% to 97.5% (Table 3); CaO2 (Fig. 3) was influenced in a similar way (16.7 ml/dl to 17.4 ml/dl).(ABSTRACT TRUNCATED AT 250 WORDS)
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Case Reports
[Tube wall herniation in an Ulmer system as a cause of an intraoperative ventilation disorder].
We report an intraoperative complication caused by nitrous oxide diffusion through the inner layer of a tube of the Ulmer breathing system, which has been developed for ventilation of small children and neonates (Fig. 2a). About 40 min after intubation and mechanical ventilation with oxygen, nitrous oxide, and halothane a sudden rise in PETCO2 was noticed (Fig. 1). ⋯ Thorough inspection of the tubes of the Ulmer breathing system revealed a herniation that nearly occluded the lumen (Fig. 2b). After changing the anesthetic system, the operation and anesthesia were continued uneventfully.