Der Anaesthesist
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The influence of halothane on the release of noradrenaline from synpathetic nerve endings was studied in isolated rabbit hearts with an intact postganglionic sympathetic nerve supply. In addition we investigated the influence of this anaesthetic on the effects of noradrenaline released from the nerve endings or infused into the aortic cannula. Halothane did not alter the noradrenaline release evoked by electrical stimulation of the postganglionic sympathetic nerve fibres. ⋯ The coronary flow decreased during application of halothane. Both stimulation of postganglionic sympathetic nerve fibres and noradrenaline infusion (250ng/min, lasting for 2 min) evoked a decline in coronary flow; the decrease in coronary flow caused by noradrenaline was markedly attenuated by halothane. This effect of halothane did probably not depend on alterations of the myocardial component of coronary resistance, but on the fact that the vasoconstrictor effect of noradrenaline on the coronary vessels was decreased by this anaesthetic.
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Randomized Controlled Trial Comparative Study Clinical Trial
[Comparative investigations on the duration and degree of action of bupivacaine and the new long acting local anaesthetic etidocaine (author's transl)].
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Randomized Controlled Trial Clinical Trial
[The mucolytic effect of Mesna].