American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · May 2013
Widespread colonization of the lung by Tropheryma whipplei in HIV infection.
Lung infections caused by opportunistic or virulent pathogens are a principal cause of morbidity and mortality in HIV infection. It is unknown whether HIV infection leads to changes in basal lung microflora, which may contribute to chronic pulmonary complications that increasingly are being recognized in individuals infected with HIV. ⋯ Asymptomatic subjects with HIV infection have unexpected colonization of the lung by T. whipplei, which is reduced by effective antiretroviral therapy and merits further study for a potential pathogenic role in chronic pulmonary complications of HIV infection.
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Am. J. Respir. Crit. Care Med. · May 2013
Catch-up alveolarization in ex-preterm children: evidence from (3)He magnetic resonance.
Histologic data from fatal cases suggest that extreme prematurity results in persisting alveolar damage. However, there is new evidence that human alveolarization might continue throughout childhood and could contribute to alveolar repair. ⋯ Alveolar size at school age was similar in survivors of extreme prematurity and term-born children. Because extreme preterm birth is associated with deranged alveolar structure in infancy, the most likely explanation for our finding is catch-up alveolarization.
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Am. J. Respir. Crit. Care Med. · May 2013
Letter Randomized Controlled TrialEffects of acute intermittent hypoxia on working memory in young healthy adults.