American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · May 2013
Comparative StudyCough aerosols of Mycobacterium tuberculosis predict new infection: a household contact study.
Airborne transmission of Mycobacterium tuberculosis results from incompletely characterized host, bacterial, and environmental factors. Sputum smear microscopy is associated with considerable variability in transmission. ⋯ Cough aerosols of M. tuberculosis are produced by a minority of patients with TB but predict transmission better than sputum smear microscopy or culture. Cough aerosols may help identify the most infectious patients with TB and thus improve the cost-effectiveness of TB control programs.