American journal of respiratory and critical care medicine
-
Am. J. Respir. Crit. Care Med. · Oct 2015
Multicenter StudyIncidence and Prognostic Value of the Systemic Inflammatory Response Syndrome and Organ Dysfunctions in Ward Patients.
Tools that screen inpatients for sepsis use the systemic inflammatory response syndrome (SIRS) criteria and organ dysfunctions, but most studies of these criteria were performed in intensive care unit or emergency room populations. ⋯ Almost half of patients hospitalized on the wards developed SIRS at least once during their ward stay. Our findings suggest that screening ward patients using SIRS criteria for identifying those with sepsis would be impractical.
-
Am. J. Respir. Crit. Care Med. · Oct 2015
Impact of Prolonged Exacerbation Recovery in Chronic Obstructive Pulmonary Disease.
Exacerbations are important and heterogeneous events in the natural history of chronic obstructive pulmonary disease (COPD). ⋯ Prolonged exacerbation symptomatic duration is associated with poorer health status and a greater risk of a new event. Exacerbations where lung function does not recover are associated with symptoms of viral infections and accelerated decline in FEV1.
-
Understanding the changing incidence and impact of acute kidney injury requiring dialysis in patients with severe sepsis will allow better risk stratification, design of clinical trials, and guide resource allocation. ⋯ Incidence of acute kidney injury requiring dialysis in patients with severe sepsis has increased over time; conversely, associated mortality has declined. The likelihood of demise from acute kidney injury requiring dialysis in patients with severe sepsis has also declined.
-
Am. J. Respir. Crit. Care Med. · Oct 2015
Effects of Recipient Age and Diagnosis on Health-Related Quality of Life Benefit of Lung Transplantation.
The average age of lung transplant recipients is increasing, and the mix of recipient indications for transplantation is changing. ⋯ Lung transplantation confers large HRQL benefits, which vary by recipient diagnosis, but do not differ substantially in older recipients.