American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Jul 2016
Airflow Limitation and Endothelial Dysfunction: Unrelated and Independent Predictors of Atherosclerosis.
Lower FEV1 is associated with increased prevalence of atherosclerosis; however, causal mechanisms remain elusive. ⋯ Endothelial dysfunction does not mediate the association between airflow limitation and atherosclerosis. Instead, airflow limitation and endothelial dysfunction seem to be unrelated and mutually independent predictors of atherosclerosis.