American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Jan 2017
Multicenter Study Observational StudyPeripheral Artery Disease and its Clinical Relevance in Patients with COPD in the COSYCONET Study.
Knowledge about the prevalence of objectively assessed peripheral artery disease (PAD) and its clinical relevance in patients with chronic obstructive pulmonary disease (COPD) is scarce. ⋯ In a large cohort of patients with COPD, 8.8% were diagnosed with PAD, which is higher than the prevalence in control subjects without COPD. PAD was associated with a clinically relevant reduction in functional capacity and health status.
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Am. J. Respir. Crit. Care Med. · Jan 2017
Maternal Folate Intake During Pregnancy and Childhood Asthma in a Population Based Cohort.
A potential adverse effect of high folate intake during pregnancy on children's asthma development remains controversial. ⋯ In this large prospective population-based cohort with essentially complete follow-up, pregnant women taking supplemental folic acid at or above the recommended dose, combined with a diet rich in folate, reach a total folate intake level associated with a slightly increased risk of asthma in children.