American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · May 2022
Investigating Nontuberculous Mycobacteria Transmission at the Colorado Adult Cystic Fibrosis Program.
Rationale: Healthcare-associated transmission of nontuberculous mycobacteria (NTM) among people with cystic fibrosis (pwCF) has been investigated at CF centers worldwide, with conflicting conclusions. We investigated transmission at the Colorado Adult CF Program. Objectives: To systematically investigate healthcare-associated transmission and/or acquisition of NTM to determine similarity among respiratory and environmental isolates, and to compare home residence watershed mapping among pwCF having genetically similar NTM isolates. ⋯ One M. abscessus cluster possibly had common acquisition arising from residing in the same watershed. The presence of genetically similar isolates is insufficient to demonstrate healthcare-associated NTM transmission. Standardizing epidemiologic investigation, combined with environmental sampling and watershed analysis, will improve understanding of the frequency and nature of healthcare-associated NTM transmission among pwCF.
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Am. J. Respir. Crit. Care Med. · May 2022
Editorial CommentChronic Cough in IPF: The Same Difference?