American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Jan 2025
Early vs. Delayed Switching from Controlled to Assisted Ventilation: A Target Trial Emulation.
In critically ill patients receiving invasive mechanical ventilation, switching from controlled to assisted ventilation is a crucial milestone towards ventilator liberation. The optimal timing for switching to assisted ventilation has not been studied. ⋯ Early switching from controlled to assisted ventilation is associated with shorter duration of invasive mechanical ventilation and ICU stay compared to delayed switching.
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Am. J. Respir. Crit. Care Med. · Jan 2025
Location of Care Delivery for Pulmonary Arterial Hypertension in the United States.
Guidelines recommend patients with pulmonary arterial hypertension (PAH) be referred to pulmonary hypertension (PH) centers, but little is known about where care is actually delivered in the United States (US). ⋯ A minority of US patients received PAH-specific prescription from a PH center. This potential guideline discordance warrants further exploration and may require guidelines to be revisited or the health system to adapt.