Croatian medical journal
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Croatian medical journal · Dec 2013
Editorial CommentWhy should medical editors CARE about case reports?
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Croatian medical journal · Oct 2013
Epigenetic drug 5-azacytidine impairs proliferation of rat limb buds in an organotypic model-system in vitro.
To establish an organotypic in vitro model of limb bud development to verify whether epigenetic drug and teratogen 5-azacytidine (5azaC) has an effect on limb buds independent of its effects on the placenta. ⋯ Our findings, obtained outside of the maternal organism, stress the importance of compromised cell proliferation for 5azaC impact on limb buds. This investigation points to the necessity to establish alternatives to in vivo research on animals using teratogenic agents.
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Croatian medical journal · Oct 2013
Availability of mental health service providers and suicide rates in Slovenia: a nationwide ecological study.
To investigate the influence of socioeconomic factors, mental health service availability, and prevalence of mental disorders on regional differences in the suicide rate in Slovenia. ⋯ Besides unemployment, which was a very strong predictor of suicide rates, unequal availability of mental health services and quality of depressive disorder treatment may contribute to variations in suicide rates in different regions.