Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
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Clinical Trial
Intra-operative, real-time, three-dimensional ultrasound assisted positioning of catheters in the microdialysis of glial tumours.
Microdialysis allows sampling of the extra cellular fluid of normal and pathological tissues. Accurate positioning of catheters in viable, representative tumour tissue is crucial for the accuracy and effectiveness of the technique. ⋯ The accuracy of the spatial targeting was validated by pathological examination and the quality of the microdialysate was checked with ultra performance liquid chromatography-mass spectrometry. Our results indicate that intra-operative 3D-US can be used to correctly position catheters for microdialysis and allows adjustment to the catheters, when necessary, prior to the dialysis of viable target tumour tissue.
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Peritumoral edema induced by radiosurgery after the treatment of intracranial meningioma has been reported and its mechanism remains unclear. A 65-year-old woman presented with a history of intermittent dizziness. A CT scan and MRI of the brain revealed an extra-axial space-occupying lesion in the left frontal region. ⋯ Six months after SRS, this patient experienced deteriorated consciousness and general weakness. Peritumoral edema in the right temporal region was noted. We report these two patients, discuss possible causes and review the relevant literature.
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Intracranial marginal zone B-cell lymphoma presenting as a dural-based mass is rare. A 45-year-old woman who had generalized tonic-clonic seizures and speech disturbance for 6 months was referred to our hospital. Radiology suggested a subdural hematoma (SDH). ⋯ Histopathological evaluation is necessary for diagnosis. MRI cannot reliably differentiate between SDH and some dural lesions that present as diffuse infiltration. Therefore, these differential diagnoses should be considered.
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Factors predictive of neurosurgery resident or applicant choice of an academic career compared to private practice are highly desired and difficult to discern. Neither medical school choice, student induction to faculty membership, age nor gender predict academic versus private practice choice among neurosurgery residents. This study was performed to examine the role of pre-residency peer-reviewed publications (PRP) in post-residency career choice. ⋯ Graduates with at least one PRP were 1.34 times more likely to choose an academic career than graduates with no PRP. Therefore, peer-reviewed PRP are strongly associated with resident choice of an academic over private practice neurosurgery career. This information might be useful in predicting the career choices of neurosurgery residents and residency applicants.