JNMA; journal of the Nepal Medical Association
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Esophageal cancer is diagnosed usually at a locally advanced stage. Surgery alone has less optimal results and a multimodality approach has been established as the standard of care for cII-III stages of esophageal cancer. ⋯ The major difference is the selection of induction treatment. Till the results of some ongoing trials become available, most of the evidences support neoadjuvant chemoradiation followed by surgery for squamous cell carcinoma and perioperative chemotherapy and surgery for adenocarcinoma.
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JNMA J Nepal Med Assoc · Apr 2021
Case ReportsRecurrence of Avellino Corneal Dystrophy Following Penetrating Keratoplasty: A Case Report.
Granular - lattice (Avellino) corneal dystrophy is inherited in an autosomal dominant fashion which affects stroma of the cornea with recurrent erosions and decreased vision due to clouding of cornea in later stage. We reported a case of 53-year old woman presented with pain and blurring of vision of left eye for 10 days with history of right eye deep anterior lamellar dystrophy and Left eye penetrating keratoplasty 5years back for Avellino dystrophy. ⋯ A patient with recurrent corneal erosions and opacity in cornea has to be examined carefully so as not to overlook Avellino corneal dystrophy. Being a rare disorder this case has been reported to draw the attention of ophthalmologists about its recurrence following keratoplasty.
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JNMA J Nepal Med Assoc · Apr 2021
Case ReportsMisoprostol Induced Expulsion of Fetus Following Diagnosis of Anencephaly on Ultrasound: A Case Report.
Anencephaly is a condition in which there is an absence of skull and brain tissues. Absence of cranial vault mainly results because of defective neurulation. Absence of cerebral tissues may cause diminished heart size, due to decreased heart load causing various cardiac abnormalities. ⋯ A 300g fetus was delivered which confirmed the ultrasound findings. The patient was discharged with advice for intake of folic acid beginning from 3 months before conception in future pregnancies. Neural tube defects can manifest within approximately 28 days of gestation which highlights the importance of oral folic acid intake before pregnancy.
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JNMA J Nepal Med Assoc · Apr 2021
Febrile Seizure in Children Attending a Tertiary Care Centre in Western Nepal: A Descriptive Cross-sectional Study.
Understanding a child with any episode of febrile seizure is important so that special attention could be given. The objective of this study was to find the prevalence of febrile seizure in children attending a tertiary centre in western Nepal. ⋯ Simple febrile seizure was more common and the peak age of presentation was in the second year of life and more commonly in male. One third of febrile seizures were recurrent and half the children had upper respiratory tract infection as the most common etiology of fever.
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JNMA J Nepal Med Assoc · Apr 2021
Digital Radiographic Study of Gonial angle in Forensic Odontology in a Tertiary Care Centre: A Descriptive Cross-sectional Study.
Gonial angle measurements serve as an important parameter of the craniofacial complex and are usually studied on lateral cephalograms, but recently panoramic radiographs have also been used. The aim of this study is to measure the gonial angle using orthopantomogram and lateral cephalogram based on age, gender, ethnicity, and skeletal malocclusion in a tertiary care hospital. ⋯ Panoramic radiograph (left side), could be considered as a reliable tool to measure the gonial angle.