Academic radiology
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Development of imaging biomarkers often relies on their correlation with histopathology. Our aim was to compare two approaches for correlating pathology to multiparametric magnetic resonance (MR) imaging (mpMRI) for localization and quantitative assessment of prostate cancer (PCa) index tumor using whole mount (WM) pathology (WMP) as the reference. ⋯ WMP correlation is superior to SPR for accurate localization of all index lesions. The use of WMP is however not required to distinguish significant differences of mean values of quantitative MRI parameters within tumor volume.
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The purpose of this study was to evaluate the correlations between objective quantitative computed tomography (CT) measurements of the extent of emphysematous and fibrotic lesions and the results of pulmonary function tests (PFTs) in patients with combined pulmonary fibrosis and emphysema (CPFE). ⋯ In CPFE, the extent of fibrosis has a more significant impact on DLco than emphysema.
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Fluoroscopically guided lumbar puncture (FGLP) is a commonly performed procedure with increased success rates relative to bedside technique. However, FGLP also exposes both patient and staff to ionizing radiation. The purpose of this study was to determine if the use of a simulation-based FGLP training program using an original, inexpensive lumbar spine phantom could improve operator confidence and efficiency, while also reducing patient dose. ⋯ Our simulation-based FGLP curriculum resulted in improved operator confidence and reduced FT. These changes suggest that resident procedure efficiency was improved, whereas patient dose was reduced. The FGLP training program was implemented by radiology residents and required a minimal investment of time and resources. The LP spine phantom used during training was inexpensive, durable, and effective. In addition, the phantom is compatible with multiple modalities including fluoroscopy, computed tomography, and ultrasound and could be easily adapted to other applications such as facet injections or joint arthrograms.
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The Lung Image Database Consortium (LIDC) and Image Database Resource Initiative (IDRI) is the largest publicly available computed tomography (CT) image reference data set of lung nodules. In this article, a comprehensive data analysis of the data set and a uniform data model are presented with the purpose of facilitating potential researchers to have an in-depth understanding to and efficient use of the data set in their lung cancer-related investigations. ⋯ This study demonstrates the usefulness of the proposed software tool to the potential users for an in-depth understanding of the LIDC/IDRI data set, therefore likely to be beneficial to their future investigations. The analysis results also demonstrate the distribution diversity of nodules characteristics, therefore being useful as a reference resource for assessing the performance of a new and existing nodule detection and/or segmentation schemes.
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To implement a preprocedural checklist in gastrointestinal (GI)/genitourinary (GU) fluoroscopy suites to assist radiology residents in performing studies with optimal fluoroscopic technique with a goal to lower radiation dose delivered to patients and operators. ⋯ A visual preprocedural radiation safety checklist in GI/GU fluoroscopy was associated with a reduction in mean FT and may contribute to a culture of radiation safety awareness.