European journal of emergency medicine : official journal of the European Society for Emergency Medicine
-
The aim of this study was to determine the outcome of patients with severe sepsis and septic shock who did and did not receive early goal-directed therapy (EGDT) in the emergency department (ED). The primary end point was the in-hospital mortality rate. The secondary end points were lengths of stay in the ICU and in hospital. ⋯ Initiating EGDT in the ED in patients with severe sepsis and septic shock was associated with a significant reduction in in-hospital mortality and length of stay in ICU.
-
The service reorganization is a part of the healthcare system reform. Some hospitals may not be able to provide all services in a 24-h basis. This evaluation was on all night-time (22 : 00 p.m. to 07 : 00 a.m.) interfacility transport by Alice Ho Miu Ling Hospital emergency department from January 2008 to December 2010, which were in-patients from nonemergency wards. ⋯ The total service time ranged from 40 to 115 min. In conclusion, en-route adverse event was not rare. The specialized team can act as a facilitator and coordinator to improve the safety and effectiveness of the whole process.
-
Previous literature suggests statins may have a therapeutic role in sepsis. No data have examined if statin use may have a positive impact beyond that afforded by early goal directed therapy (EGDT). ⋯ Prior statin use is associated with fewer mechanical ventilation days and a trend toward improvement in other clinically relevant outcomes. This trial is limited by its retrospective nature and small sample size. These results should serve as hypothesis generating for future prospective trials, as the lack of novel drug therapy and the mortality rate of septic shock both remain unacceptable.