Journal of investigative medicine : the official publication of the American Federation for Clinical Research
The most recent articles from:
J. Investig. Med.
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Biography Historical Article
Issues in developing the medical scientist, part 1: interview with Dr. Robert W. Schrier, MD.
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Randomized Controlled Trial Comparative Study Clinical Trial
Effects of atorvastatin and simvastatin on low-density lipoprotein subfraction profile, low-density lipoprotein oxidizability, and antibodies to oxidized low-density lipoprotein in relation to carotid intima media thickness in familial hypercholesterolemia.
Little is known about the effects of statins on the quality of circulating low-density lipoprotein (LDL) in relation to atherosclerosis progression. ⋯ Change of IMT after statin treatment was associated with baseline IMT (r = .41), LDL cholesterol (r = -.20), and the amount of dienes formed during in vitro oxidation of LOL (r = .28) but not with plasma levels of antibodies to oxidized LDL, in vitro LDL oxidizability, and LDL subfraction profile.