Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · May 2021
Resuscitation of non-vigorous neonates born through meconium-stained amniotic fluid: post policy change impact analysis.
We investigated the impact of policy change in delivery room resuscitation from routine endotracheal (ET) suctioning of non-vigorous neonates born through meconium-stained amniotic fluid (MSAF) to immediate non-invasive respiratory support. ⋯ The policy change towards not routinely suctioning non-vigorous neonates born through MSAF at birth was not associated with an increase in the local incidence of MAS and was associated with fewer NICU admissions.
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Arch. Dis. Child. Fetal Neonatal Ed. · May 2021
ReviewCoronavirus infection in neonates: a systematic review.
To summarise currently reported neonatal cases of SARS-CoV-2 infection. ⋯ Most neonates with SARS-CoV-2 infection were asymptomatic or presented mild symptoms, generally were left in spontaneous breathing and had a good prognosis after median 10 days of hospitalisation. Large epidemiological and clinical cohort studies, as well as the implementation of collaborative networks, are needed to improve the understanding of the impact of SARS-CoV-2 infection in neonates.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 2021
Meta AnalysisOutcomes of endotracheal suctioning in non-vigorous neonates born through meconium-stained amniotic fluid: a systematic review and meta-analysis.
We aimed to systematically review and analyse the outcomes of non-endotracheal suctioning (non-ETS) versus ETS in non-vigorous meconium-stained neonates. ⋯ Initiating ETS soon after birth in non-vigorous meconium-stained infants may not alter their neonatal outcomes.
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2020
Meta AnalysisUmbilical cord milking in preterm infants: a systematic review and meta-analysis.
To conduct a systematic review and meta-analysis of the efficacy and safety of umbilical cord milking in preterm infants. ⋯ Umbilical cord milking, when compared with delayed cord clamping, significantly increased the risk of severe intraventricular haemorrhage in preterm infants, especially at lower gestational ages. Cord milking, when compared with immediate cord clamping, reduced the need for packed RBC transfusions but did not improve clinical outcomes. Hence, cord milking cannot be considered as placental transfusion strategy in preterm infants based on the currently available evidence.
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2020
Multicenter Study Comparative StudyComparison of the management recommendations of the Kaiser Permanente neonatal early-onset sepsis risk calculator (SRC) with NICE guideline CG149 in infants ≥34 weeks' gestation who developed early-onset sepsis.
To compare the management recommendations of the Kaiser Permanente neonatal early-onset sepsis risk calculator (SRC) with National Institute for Health and Care Excellence (NICE) guideline CG149 in infants ≥34 weeks' gestation who developed early-onset sepsis (EOS). ⋯ While both tools were poor in identifying EOS within 4 hours, NICE was superior to SRC in identifying asymptomatic cases. Currently, four out of five EOS have symptoms at first identification, the majority of whom present within 24 hours of birth. Antibiotic stewardship programmes using SRC should include enhanced observation for infants currently treated within NICE guidance.