Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · May 2013
Comparative StudyIn vitro comparison of neonatal suction catheters using simulated 'pea soup' meconium.
A variety of suction catheters (type, size and design) are recommended for oropharyngeal suctioning of meconium during newborn resuscitation, but it is not known which performs best. In this study we compared different sizes of soft catheters, the Yankauer (YK) and the portable bulb syringe (BS), in suctioning a solution of varying viscosity. ⋯ The YK and BS outperform the catheters in suctioning SM. The YK is the best for TP, but all devices perform poorly in suctioning fluid of this consistency.
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Arch. Dis. Child. Fetal Neonatal Ed. · May 2013
Avoiding sedation in research MRI and spectroscopy in infants: our approach, success rate and prevalence of incidental findings.
Performing magnetic resonance investigations in a paediatric population can be difficult; image acquisition is commonly complicated by movement artefact and non-compliance. Sedation is widely used for clinically indicated investigations, but there is controversy when used for research imaging. Over a 10-year period we have performed whole body MRI on over 450 infants and hepatic magnetic resonance spectroscopy on over 270 infants. ⋯ The prevalence of incidental findings on whole body (excluding brain) MRI in our cohort was 0.8%. We conclude that the use of sedation for research MRI in this group is not necessary. Our approach to MRI in infancy is also described.
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Arch. Dis. Child. Fetal Neonatal Ed. · Mar 2013
Multicenter Study Controlled Clinical TrialMinimally-invasive surfactant therapy in preterm infants on continuous positive airway pressure.
To evaluate the applicability and potential effectiveness of a technique of minimally-invasive surfactant therapy (MIST) in preterm infants on continuous positive airway pressure (CPAP). ⋯ Surfactant delivery via a narrow-bore tracheal catheter is feasible and potentially effective, and deserves further investigation in clinical trials.
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Arch. Dis. Child. Fetal Neonatal Ed. · Mar 2013
Comparative StudyEnd tidal carbon dioxide is as reliable as transcutaneous monitoring in ventilated postsurgical neonates.
To compare the agreement, precision and repeatability of end tidal carbon dioxide (EtCO2 ) and transcutaneous carbon dioxide (TcCO2 ) with partial pressure of arterial CO(2) ( PaCO2) in postoperative neonates. ⋯ In postoperative neonates, EtCO2 and TcCO2 demonstrated a clinically acceptable agreement with PaCO2.
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Arch. Dis. Child. Fetal Neonatal Ed. · Mar 2013
Clinical TrialTreatment of presumed hypotension in very low birthweight neonates: effects on regional cerebral oxygenation.
Previous studies have correlated poor neurological outcomes with hypotension. Treatment of hypotension in very low birthweight (VLBW) infants is common, and most often is based solely on the blood pressure measurement. Whether treatment improves cerebral oxygenation is unclear. ⋯ These results suggest that treating hypotension in VLBW neonates based solely on a blood pressure measurement of less than 30 mm Hg, while increasing blood pressure, may not increase cerebral oxygenation, possibly because many of these patients are in the autoregulatory zone for cerebral blood flow.