Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 2000
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialInternational randomised controlled trial of patient triggered ventilation in neonatal respiratory distress syndrome.
To compare the effects of patient triggered ventilation (PTV) with conventional ventilation (IMV) in preterm infants ventilated for respiratory distress syndrome (RDS). ⋯ There was no observed benefit from the use of PTV, with a trend towards a higher rate of pneumothorax under 28 weeks of gestation. Although PTV has a similar outcome to IMV for treatment of RDS in infants of 28 weeks or more gestation, within 72 hours of birth, it was abandoned more often. It cannot be recommended for infants of less than 28 weeks' gestation with the ventilators used in this study.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 2000
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialRandomised controlled trial of patient triggered and conventional fast rate ventilation in neonatal respiratory distress syndrome.
To compare patient triggered, with conventional fast rate, ventilation in a randomised controlled trial using the incidence of chronic lung disease as the primary outcome measure. ⋯ Patient triggered ventilation in preterm infants with respiratory distress syndrome is feasible. No significant differences, when compared with conventional fast rate ventilation in important medium and longer term outcome measures, were evident.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 2000
Randomized Controlled Trial Comparative Study Clinical TrialRandomised controlled trial of thiopental for intubation in neonates.
To determine the effects of premedication with thiopental on heart rate, blood pressure, and oxygen saturation during semi-elective nasotracheal intubation in neonates. ⋯ The heart rate and blood pressure of infants who are premedicated with thiopental are maintained nearer to baseline values than those of similar infants who receive no premedication. Whether this lessening of the acute drop in the heart rate and increase in blood pressure typically seen during intubation of unmedicated infants is associated with long term advantages to the infants remains to be determined.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 2000
Randomized Controlled Trial Comparative Study Clinical TrialRandomised controlled study of clinical outcome following trophic feeding.
To determine the effect of trophic feeding on clinical outcome in ill preterm infants. ⋯ Trophic feeding improves clinical outcome in ill preterm infants requiring parenteral nutrition.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 2000
Premedication before intubation in UK neonatal units.
To establish the extent and type of premedication used before intubation in neonatal units in the United Kingdom. ⋯ Most UK neonatal units do not sedate babies before intubating, despite evidence of physiological and practical benefits. Only a minority have written guidelines, which prohibits auditing of practice.