American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
-
Am J Health Syst Pharm · Aug 2010
ReviewUse of granulocyte colony-stimulating factor in patients with severe sepsis or septic shock.
The efficacy and safety of granulocyte colony-stimulating factor (G-CSF) in critically ill patients with severe sepsis or septic shock were evaluated. ⋯ The available data, especially those from large, prospective, randomized, double-blind studies, do not support the use of G-CSF as an adjunct therapy to standard care for critically ill patients with severe sepsis or septic shock. Data from prospective, large, randomized, controlled, well-designed studies are needed to define the optimal G-CSF dosing regimen, the safety of this therapy, and the effects of G-CSF on patient morbidity and survival.
-
Am J Health Syst Pharm · Aug 2010
ReviewSignificant publications on infectious diseases pharmacotherapy in 2009.
Significant publications on infectious diseases (ID) pharmacotherapy in 2009 are summarized. ⋯ Due to the growing number of articles published each year, it is difficult to maintain a current knowledge of significant publications in ID. This review of significant publications in ID pharmacotherapy can be helpful by lessening this burden.
-
Am J Health Syst Pharm · Aug 2010
Effects of clinical decision support on venous thromboembolism risk assessment, prophylaxis, and prevention at a university teaching hospital.
The implementation of a mandatory assessment of risk for venous thromboembolism (VTE) in a health system's electronic medical record (EMR) and clinical decision-support (CDS) system was evaluated to measure its effect on the use of pharmacologic prophylaxis and the occurrence of VTE and bleeding events. ⋯ Without increasing the risk of bleeding, a CDS system requiring clinicians to document VTE risk assessment in the EMR promoted improved rates of pharmacologic prophylaxis at any time during an admission and a decreased risk of VTE in general medical patients but not all adult patients.
-
Am J Health Syst Pharm · Aug 2010
Case ReportsCase report: a 55-year-old woman with chest pain upon arrival to the emergency department.
The case of a woman with progressive substernal chest pain is described. ⋯ Discussion of a patient with non-ST elevation ACS illustrates some of the clinical issues surrounding PCI and stent implantation, including selection and use of antiplatelet therapy.