American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
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Am J Health Syst Pharm · Sep 2011
Randomized Controlled Trial Comparative StudyEffect of ascorbic acid on inflammatory markers after cardiothoracic surgery.
The effect of ascorbic acid on inflammatory markers after cardiothoracic surgery (CTS) was studied. ⋯ Ascorbic acid did not attenuate the rise in inflammatory markers after CTS when compared with placebo. The use of off-pump surgery did not significantly change the levels of CRP and fibrinogen or the WBC count postoperatively when compared with on-pump surgery with a biocompatible polymer coating.