American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
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Am J Health Syst Pharm · Feb 2008
Letter Clinical TrialExtended-release epidural morphine and postoperative nausea or vomiting.
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Am J Health Syst Pharm · Jan 2008
ReviewRecent developments in the management of acute respiratory distress syndrome in adults.
Recent developments in the management of acute respiratory distress syndrome (ARDS) in adults are reviewed. ⋯ Early administration of moderate-dosage corticosteroids likely helps decrease the time of ventilator dependence and duration of intensive care unit stay. Conservative fluid management and low tidal volume ventilation are becoming increasingly widespread in the management of patients with ARDS. Nitric oxide, surfactant, prostaglandins, albuterol, acetylcysteine, and prone positioning have not been shown to be beneficial in the treatment of ARDS.
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Am J Health Syst Pharm · Dec 2007
Comparative StudyStability of codeine phosphate in an extemporaneously compounded syrup.
The stability of codeine phosphate in an extemporaneously compounded syrup is described. ⋯ Codeine phosphate 3 mg/mL in Ora-Sweet syrup vehicle was stable in both amber polyethylene terephthalate bottles and amber polyethylene oral syringes for at least 98 days when stored at 22-25 degrees C and protected from light.
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Am J Health Syst Pharm · Dec 2007
Review Comparative StudyNew strategies in controlling drug resistance in chronic myeloid leukemia.
Imatinib has been quite effective in maintaining patients with CML in the chronic phase (CP); however, some patients develop imatinib resistance. This review addresses the mechanisms underlying imatinib resistance and the strategies currently being used to overcome that resistance. ⋯ A better understanding of imatinib resistance mechanisms has resulted in the development of useful strategies both to predict responders and nonresponders and to minimize imatinib resistance and prolong the life of the patient.