American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
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Am J Health Syst Pharm · Aug 2004
ReviewAcute postoperative hypertension: a review of therapeutic options.
The pathophysiology and treatment of acute postoperative hypertension (APH) are discussed. ⋯ When treatment of APH is necessary, therapy should be individualized for the patient. No one agent is preferred, but effective options include sodium nitroprusside, nitroglycerin, labetalol, and nicardipine.
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Am J Health Syst Pharm · Aug 2004
Comparative StudyStability of meropenem in polyvinyl chloride bags and an elastomeric infusion device.
The stability of meropenem in i.v. solutions stored in polyvinyl chloride (PVC) bags and an elastomeric infusion device at concentrations commonly used in home care was studied. ⋯ Meropenem 4 mg/mL in NS was stable for at least seven days in PVC bags and elastomeric infusion containers when stored at 5 degrees C, and meropenem 10 and 20 mg/mL in NS was stable for at least five days in both containers at 5 degrees C.
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The incidence of adverse drug events (ADEs), preventable ADEs, and potential ADEs was determined using pharmacist surveillance. Drug classes associated with ADEs were also identified. ⋯ Pharmacist surveillance revealed that 4.4 ADEs occurred per 100 patient-days, over half of which were preventable. All preventable and potential ADEs occurred during the ordering and administration stages of medication delivery.
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Am J Health Syst Pharm · Jul 2004
ReviewOmalizumab: a recombinant humanized anti-IgE antibody for allergic asthma.
The pharmacology, efficacy, dosage, adverse events, and economics of omalizumab are discussed. ⋯ Omalizumab should be considered as a second-line therapy for patients with moderate to severe persistent allergic asthma.