American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
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Am J Health Syst Pharm · Mar 2018
Establishment of a pharmacist-led service for patients at high risk for opioid overdose.
A program at a family medicine clinic to provide naloxone prescriptions in conjunction with education on naloxone use and opioid hazards to patients at risk for opioid overdose is described. ⋯ Naloxone prescribing and provision of education on naloxone use to at-risk patients in a family medicine clinic can help ensure access to life-saving medication and reinforce CDC recommendations on safe prescribing of opioids.
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Am J Health Syst Pharm · Mar 2018
Case Reports Observational StudyEffect of a single dose of i.v. ondansetron on QTc interval in emergency department patients.
Results of a study to determine whether i.v. administration of a single dose of 4 mg of ondansetron was associated with QT interval prolongation in emergency department (ED) patients are reported. ⋯ Significant QTc prolongation occurred in ED patients receiving a single 4-mg i.v. dose of ondansetron. None of the patients had an ondansetron-related cardiac adverse event.
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Am J Health Syst Pharm · Mar 2018
Observational StudyPatient nonadherence to filling discharge medication prescriptions from the emergency department: Barriers and clinical implications.
Barriers to and clinical implications of patient nonadherence to filling discharge medication prescriptions from the emergency department (ED) were evaluated. ⋯ The majority of patients who received a prescription during an ED visit filled their discharge medications. Sex, ethnicity, and payer class were independently associated with nonadherence.
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Am J Health Syst Pharm · Mar 2018
Observational StudyAssociation between continuous peripheral i.v. infusion of 3% sodium chloride injection and phlebitis in adults.
One institution's experience with use of peripheral i.v. (PIV) catheters for prolonged infusions of 3% sodium chloride injection at rates up to 100 mL/hr is described. ⋯ Patient and catheter phlebitis rates were not significantly different with infusions of 3% sodium chloride injection versus RCSs, suggesting that an osmolarity cutoff value of 900 mOsm/L for peripheral infusions of hypertonic saline solutions may not be warranted.
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Am J Health Syst Pharm · Mar 2018
Using lean methodology to optimize time to antibiotic administration in patients with sepsis.
Results of a study to apply lean methodology to an inpatient pharmacy workflow to optimize timely administration of Centers for Medicare and Medicaid Services (CMS)-approved antibiotics for patients with severe sepsis or septic shock are presented. ⋯ Lean methodology was successfully used to reduce time to antibiotic administration, which led to improved compliance with the newly implemented sepsis CMS core measure.