American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
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Am J Health Syst Pharm · Aug 2016
Implementation of an emergency department-based clinical pharmacist transitions-of-care program.
The implementation of an emergency department (ED)-based clinical pharmacist transitions-of-care (TOC) program is described. ⋯ A TOC pharmacist-led program targeting patients who arrived at the ED with the chief complaint of asthma exacerbation, COPD, or CHF provided interventions from an ED or ambulatory care pharmacist as well as follow-up opportunities at outpatient clinics or an HBMM program.
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Am J Health Syst Pharm · Jul 2016
ReviewOlaparib for the treatment of BRCA-mutated advanced ovarian cancer.
The pharmacology, clinical efficacy, safety, dosage and administration, and role in therapy of olaparib, a first-in-class treatment for advanced treatment-refractory ovarian cancer, are reviewed. ⋯ Olaparib is a novel PARP inhibitor that is efficacious and well tolerated in patients with BRCA-mutated advanced ovarian cancers who have received three or more lines of prior treatment.
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Am J Health Syst Pharm · Jun 2016
ReviewPharmacologic management of angioedema induced by angiotensin-converting enzyme inhibitors.
The published evidence on pharmacologic approaches to the management of angiotensin-converting enzyme inhibitor (ACEI)-induced angioedema is reviewed. ⋯ FFP, C1 inhibitor, and icatibant appear to be safe and effective therapeutic options for the management of ACEI-induced angioedema, whereas it appears ecallantide should be avoided.
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Am J Health Syst Pharm · Jun 2016
Opioid prescription fill rates after emergency department discharge.
Opioid prescription fill rates and the time to fill after emergency department (ED) discharge were studied. ⋯ One in five patients who received an opioid prescription at discharge from an urban academic ED did not fill it. Several factors may be associated with a greater likelihood of filling, such as insurance status and history of filling an opioid prescription within the past year.