American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
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Am J Health Syst Pharm · Aug 2012
ReviewA new epoprostenol formulation for the treatment of pulmonary arterial hypertension.
The pharmacology and pharmacokinetics of a novel formulation of epoprostenol for the treatment of pulmonary arterial hypertension (PAH) are reviewed, with guidance on addressing a number of important safety considerations. ⋯ Veletri provides an epoprostenol therapy option that reduces some of the inconveniences of the other formulation. Drug stability is dependent on cassette concentrations, which may be limited by sterility concerns with outpatient preparation. Use of this new agent within the health system requires an evaluation of practices to ensure patient safety.
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Am J Health Syst Pharm · Aug 2012
Comparative StudyExemestane for primary prevention of breast cancer in postmenopausal women.
The benefits and risks of exemestane for the primary prevention of breast cancer are discussed and compared with other breast cancer chemoprevention therapies. ⋯ Exemestane 25 mg daily taken for at least three years is a new option for the prevention of breast cancer in high-risk postmenopausal women. Indirectly compared with SERMs, exemestane has a similar frequency of bothersome adverse effects without the risk of thromboembolic events or endometrial cancer, though an increased risk of osteoporosis is of concern.
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Am J Health Syst Pharm · Aug 2012
Survey of learning opportunities in academia for pharmacy residents.
The types of teaching experiences offered in academia in pharmacy residency programs affiliated with or offered through colleges of pharmacy throughout the United States were evaluated. ⋯ The majority of PGY1 and PGY2 residency programs surveyed did not offer concentrated rotations in academia but did offer longitudinal opportunities for residents to gain teaching experience. The majority of programs that did not offer these experiences did want formal training on how to provide these opportunities.