American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
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Am J Health Syst Pharm · Sep 2009
Coagulation factor VIIa (recombinant) in nonhemophilic patients requiring neurosurgery.
The clinical outcomes, safety, and use of resources associated with the administration of factor VIIa (recombinant) to nonhemophilic patients requiring neurosurgery were evaluated. ⋯ A protocol calling for administration of factor VIIa (recombinant) 40 microg/kg in nonhemophilic patients with coagulopathy and ICH led to a rapid and significant decrease in the INR, allowing for emergency surgical intervention. Few adverse events were detected in these patients, and none were deemed to be directly related to factor VIIa (recombinant).
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Am J Health Syst Pharm · Aug 2009
Expansion of pharmacists' responsibilities in an emergency department.
The role of pharmacists in the emergency department (ED) of an acute care hospital is described. ⋯ ED pharmacists at one institution expanded their clinical role by taking on more direct patient care responsibilities. Pharmacists' interventions were well received by ED physicians, with an acceptance rate of 98%.