Investigative radiology
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Investigative radiology · Aug 2015
Quantitative Susceptibility Mapping at 3 T and 1.5 T: Evaluation of Consistency and Reproducibility.
The aim of this study was to assess the consistency and reproducibility of quantitative susceptibility mapping (QSM) at 3-T and 1.5-T magnetic resonance (MR) scanners. ⋯ Quantitative susceptibility mapping with HARPERELLA and V-SHARP demonstrated good reproducibility at 3 T and 1.5 T, and QSM with V-SHARP demonstrated good consistency at 3 T and 1.5 T.
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Investigative radiology · Aug 2015
Comparative StudyPositron Emission Tomography/Magnetic Resonance Imaging for Local Tumor Staging in Patients With Primary Breast Cancer: A Comparison With Positron Emission Tomography/Computed Tomography and Magnetic Resonance Imaging.
This study aimed to assess the diagnostic performance of integrated positron emission tomography (PET)/magnetic resonance imaging (MRI) of the breast for lesion detection and local tumor staging of patients with primary breast cancer in comparison to PET/computed tomography (CT) and MRI. ⋯ Integrated PET/MRI does not provide diagnostic advantages for local tumor staging of breast cancer patients in comparison to MRI alone. Positron emission tomography/MRI and MRI enable an improved determination of the local tumor extent in comparison to PET/CT, whereas all 3 imaging modalities offer a comparable diagnostic performance for the identification of axillary disease.
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Investigative radiology · Jul 2015
Incorporation of Time-of-Flight Information Reduces Metal Artifacts in Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging: A Simulation Study.
This study aimed to describe and evaluate the influence of time-of-flight (TOF) information on metal artifact reduction in positron emission tomography (PET) image quality in clinical simultaneous PET/magnetic resonance (MR) scanning. ⋯ Positron emission tomographic imaging benefits from the integration of TOF information in simultaneous PET/MR. The inclusion of TOF information in simultaneous PET/MR imaging reduces errors related to metal artifacts at the site of the artifact.
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Investigative radiology · Jul 2015
Computed Tomography Angiography With High Flow Rates: An In Vitro and In Vivo Feasibility Study.
The aims of this study were to test high-flow application of contrast media (CM) using novel high-flow needles and to assess injection- and flow-related parameters in a circulation phantom and in an in vivo population. ⋯ These results indicate that injections with 9 mL/s using high-flow injection needles are safe. The pressure limit of 325 psi was not reached, and the injections resulted in diagnostic attenuation values. Using this dedicated needle, high flow rates should not be considered a drawback for CM application in routine CT angiography examinations.
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Investigative radiology · Jul 2015
Real-Time In Vivo Characterization of Primary Liver Tumors With Diffuse Optical Spectroscopy During Percutaneous Needle Interventions: Feasibility Study in Woodchucks.
This study presents the first in vivo real-time optical tissue characterization during image-guided percutaneous intervention using near-infrared diffuse optical spectroscopy sensing at the tip of a needle. The goal of this study was to indicate transition boundaries from healthy tissue to tumors, namely, hepatic carcinoma, based on the real-time feedback derived from the optical measurements. ⋯ Tissue blood content, oxygenation level, lipid content, and tissue density all showed significant differences when the needle tip was guided from the healthy tissue to the carcinoma and can therefore be used to identify tissue boundaries during percutaneous image-guided interventions.