Investigative radiology
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Magnetic resonance angiography (MRA) is noninvasive and does not require the application of high doses of contrast agents, and thus is used in the clinical routine for evaluation of cerebrovascular diseases, eg, aneurysm and arteriovenous malformations. However, more subtle microvascular disease usually cannot be seen with the resolution capabilities of standard field strength MRA. The purpose of this study was to evaluate the ability of 7-T time-of-flight (ToF) MRA to depict the arterial brain vasculature and to compare the results to data from 1.5 T and 3 T. ⋯ Because of its considerably enhanced potential to depict vessels of the Circle of Willis and its first- and second-order branches, ToF MRA at 7 T may become an important tool in future neuroradiology research and clinical care.
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Investigative radiology · Aug 2008
Comparative StudyFollow-up of coiled cerebral aneurysms: comparison of three-dimensional time-of-flight magnetic resonance angiography at 3 tesla with three-dimensional time-of-flight magnetic resonance angiography and contrast-enhanced magnetic resonance angiography at 1.5 Tesla.
To compare three-dimensional (3D) time-of-flight (TOF)-magnetic resonance angiography (MRA) at 3 T with 3D TOF-MRA and ultrafast contrast-enhanced (CE)-MRA at 1.5 T and to determine the optimum MRA sequence for follow-up of cerebral aneurysms treated with Guglielmi detachable coils (GDCs). ⋯ TOF-MRA follow-up of coiled aneurysms is better at 3 T than at 1.5 T; nevertheless, greater definition of residual patency is achieved with ultrafast CE-MRA at 1.5 T.
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Investigative radiology · Jul 2008
Randomized Controlled TrialContrast injection protocols for coronary computed tomography angiography using a 64-detector scanner: comparison between patient weight-adjusted- and fixed iodine-dose protocols.
To compare patient-weight-adjusted and fixed iodine-dose protocols at coronary computed tomography angiography (CTA) using a 64-detector scanner and computer-assisted bolus tracking. ⋯ At 64-detector CTA of the heart, the patient weight-tailored dose protocol with the 15-second injection duration yielded significantly better image quality than the fixed-dose, 20-second injection duration protocol.
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Investigative radiology · Jul 2008
Evaluation of normal prostate tissue, chronic prostatitis, and prostate cancer by quantitative perfusion analysis using a dynamic contrast-enhanced inversion-prepared dual-contrast gradient echo sequence.
To quantify independent pharmacokinetic parameters for differentiation of prostate pathology. ⋯ The pharmacokinetic parameters investigated, especially perfusion, allow statistically significant in situ differentiation of normal prostate tissue from cancer and chronic prostatitis and of high-grade cancer from chronic prostatitis.
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Investigative radiology · Jun 2008
Comparative StudyComparison of radiologist and CAD performance in the detection of CT-confirmed subtle pulmonary nodules on digital chest radiographs.
Detection of subtle pulmonary nodules on digital radiography is a challenging task for radiologists. The aim of this study was to evaluate the performance of a newly approved computer aided detection (CAD) system. ⋯ The CAD system's diagnostic sensitivity in detecting pulmonary nodules of 5 to 15 mm of size was superior to the 1 of radiologists. The CAD system may be used for assisting the radiologist in the detection of lung nodules on digital chest radiographs.