Investigative radiology
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Investigative radiology · Jun 2007
High-resolution magnetic resonance imaging (MRI) at 3.0 Tesla in the short-term follow-up of patients with proven cervical artery dissection.
For the imaging evaluation of patients with suspected cervical artery dissection (CAD) in the last decade, magnetic resonance imaging (MRI) has become the first line imaging modality. However, CAD is a highly dynamic process with rapid changes over time. Aim of this study was to assess the short-term morphologic changes in patients with proven CAD by MRI within 2 weeks after the initial diagnosis using a multicontrast high-resolution noninvasive vessel wall imaging approach at 3.0 T. ⋯ High-resolution MRI of acute CAD at 3.0 T permits a refined cross-sectional and longitudinal analysis of the morphologic features of CAD. The increased signal-to-noise ratio at 3.0 T allows for a high spatial resolution permitting detailed analysis of the diseased vessel segment. An unequivocal distinction between intramural hematoma and thrombus was possible. Information could be gained with regard to recanalization, degree of stenosis, formation of pseudoaneurysm, and appearance of new dissections making short-term follow-up in pts with acute CAD recommendable. Further studies are needed to assess the relationship between short-term results and definite outcome.
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Investigative radiology · Apr 2007
Potential of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) for differential diagnosis of nonalcoholic steatohepatitis and fatty liver in rats using magnetic resonance imaging.
To investigate the potential of gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) for the differential diagnosis of nonalcoholic steatohepatitis (NASH) and fatty liver (FL). ⋯ It was possible to differentiate NASH and FL by evaluating the SI time course on Gd-EOB-DTPA enhanced MRI.
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Investigative radiology · Mar 2007
Effect of the arterial input function on the measured perfusion values and infarct volumetric in acute cerebral ischemia evaluated by perfusion computed tomography.
We sought to evaluate the accuracy of the perfusion computed tomography (PCT) deconvolution-based brain perfusion measurements and the lesions' (infarct and penumbra) volumetric with regard to arterial input function (AIF) selection in patients with acute stroke. ⋯ The AIF selection in the ACA as well as in the ipsilateral (to the hypoperfused area) or contralateral branches of the MCA has no statistically significant impact on the calculation of the CBF, CBV values, and the volume estimation of the ischemic region in the acute stroke patients.
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Investigative radiology · Mar 2007
Switching monopolar radiofrequency ablation technique using multiple, internally cooled electrodes and a multichannel generator: ex vivo and in vivo pilot study.
We sought to determine the optimal switching time and interprobe distance for creating a large coagulation zone in the liver by switching monopolar radiofrequency ablation (RFA) technique using a prototype multichannel radiofrequency generator and multiple electrodes. ⋯ Our study demonstrated that switching monopolar RFA using the multichannel RF system at a 2- or 3-cm interprobe distance and at a 30-second switching time can create a large, confluent coagulation zone in the liver within a clinically acceptable time frame. We believe that this technology will provide a useful tool for the treatment of large liver tumors.
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Investigative radiology · Feb 2007
Randomized Controlled TrialEvaluation of a novel time-efficient protocol for gadobenate dimeglumine (Gd-BOPTA)-enhanced liver magnetic resonance imaging.
We sought to evaluate gadobenate dimeglumine for the detection and characterization of focal liver lesions in the unenhanced and already pre-enhanced liver. ⋯ Dynamic imaging in the hepatobiliary phase gives similar information as dynamic imaging of the unenhanced liver. This might prove advantageous for screening protocols involving same session imaging of primary extrahepatic tumors and liver.