Investigative radiology
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Investigative radiology · Oct 2006
Clinical TrialThree-dimensional cerebral contrast-enhanced magnetic resonance venography at 3.0 Tesla: initial results using highly accelerated parallel acquisition.
The objective of this study was to evaluate a high spatial resolution 3-dimensional (3D) contrast-enhanced magnetic resonance (CE-MR) venography protocol for evaluation of intracranial venous system using highly accelerated parallel imaging at 3.0 T. ⋯ High spatial resolution 3D cerebral CE-MR venography is feasible and promising. Using a 32-channel 3.0 T system combined with multichannel array coils effectively supports highly accelerated parallel imaging, enabling subsequent acquisition of both high spatial resolution CE-MR angiography and CE-MR venography after a single contrast injection without impairing the image quality. More extensive clinical studies are warranted to establish the range of applications and confirm the accuracy of this technique.
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Investigative radiology · Sep 2006
Comparative Study Clinical TrialAssessment of myocardial viability using delayed enhancement magnetic resonance imaging at 3.0 Tesla.
Cardiac magnetic resonance imaging (MRI) at 3.0 T has recently become available and potentially provides a significant improvement of tissue contrast in T1-weighted imaging techniques relying on Gd-based contrast enhancement. Imaging at high-field strength may be especially advantageous for methods relying on strong T1-weighting and imaging after contrast material administration. The aim of this study was to compare cardiac delayed enhancement (DE) MRI at 3.0 T and 1.5 T with respect to image quality, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) between infarcted and normal myocardium. ⋯ Delayed enhancement MRI at 3.0 T is feasible and provides superior image quality compared with 1.5 T. Furthermore, using identical contrast doses, increased SNR and CNR values were recorded at 3.0 T.
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Investigative radiology · Sep 2006
Comparative StudyComparison of different radiography systems in an experimental study for detection of forearm fractures and evaluation of the Müller-AO and Frykman classification for distal radius fractures.
We sought to compare the diagnostic performance of screen-film radiography, storage-phosphor radiography, and a flat-panel detector system in detecting forearm fractures and to classify distal radius fractures according to the Müller-AO and Frykman classifications compared with the true extent, depicted by anatomic preparation. ⋯ The 3 imaging systems showed a comparable diagnostic performance in detecting forearm fractures. A high diagnostic performance was demonstrated for distal radius fractures and conventional radiography can be routinely performed for fracture detection. However, compared with anatomic preparation, depiction of the true extent of distal radius fractures was limited and the severity of distal radius fractures tends to be underestimated.
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Investigative radiology · Sep 2006
Renal magnetic resonance angiography at 3.0 Tesla using a 32-element phased-array coil system and parallel imaging in 2 directions.
The aim of the present study was to assess the feasibility of renal magnetic resonance angiography at 3.0 T using a phased-array coil system with 32-coil elements. Specifically, high parallel imaging factors were used for an increased spatial resolution and anatomic coverage of the whole abdomen. ⋯ MRA at 3.0 T using a 32-element phased-array coil is feasible in healthy volunteers. High diagnostic image quality and extended anatomic coverage could be achieved with application of high parallel imaging factors.
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Investigative radiology · Aug 2006
Osteosarcoma: preliminary results of in vivo assessment of tumor necrosis after chemotherapy with diffusion- and perfusion-weighted magnetic resonance imaging.
We sought to evaluate diffusion and perfusion weighted 1.5 T magnetic resonance imaging (MRI) in detecting tumor necrosis with histologic correlation after preoperative chemotherapy. ⋯ Both dynamic contrast-enhanced MRI and diffusion-weighted MRI permit recognition of tumor necrosis induced by chemotherapy in osteosarcomas. We hypothesized that diffusion-weighted imaging is correlated directly with tumor necrosis. Perfusion-weighted imaging is correlated with microvessel density, vascular permeability, local blood volume, and flow. Therefore, perfusion weighed MRI depicts areas of tumor cell necrosis indirectly.