European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
-
Eur J Vasc Endovasc Surg · Jul 1996
Clinical Trial Controlled Clinical TrialPeripheral arterial occlusions: local low-dose thrombolytic therapy with recombinant tissue-type plasminogen activator (rt-PA).
To study the efficacy and risks of local thrombolytic therapy of peripheral arterial occlusions using rt-PA. ⋯ The use of rt-PA for local lysis substitutes the inadequate tissue activator available for effective spontaneous lysis and is, therefore, almost physiological. The effect of a very low dose of rt-PA was as good as that of higher doses.
-
Eur J Vasc Endovasc Surg · Apr 1996
Comparative StudyIntraoperative duplex scanning as a means of quality control during carotid endarterectomy.
To identify correctable technical errors following carotid endarterectomy using intraoperative colour duplex sonography (ATL, UM9, HDI). Results were compared with intraoperative flow measurements using an operative flow meter and with middle cerebral artery velocity measured by trans-cranial Doppler (TCD). ⋯ Duplex sonography provides a sensitive intraoperative technique for detecting thrombus and technical errors. It yields both anatomic and hemodynamic details and is superior to intraoperative flow measurements and transcranial doppler.
-
Eur J Vasc Endovasc Surg · Feb 1996
Comparative StudyGastric intramucosal pH predicts outcome after surgery for ruptured abdominal aortic aneurysm.
The mortality associated with repair of ruptured abdominal aortic aneurysms (RAAA) remains obstinately high and many deaths result from multiple organ failure which is likely to be related to splanchnic ischaemia. The aim of this study is to investigate the importance of splanchnic ischaemia in determining outcome from RAAA by comparing gastric intramucosal pH with other methods of assessing the adequacy of splanchnic oxygenation. ⋯ Gastric intramucosal pH is the most reliable indicator of adequacy of tissue oxygenation in patients with RAAA, suggesting that splanchnic ischaemia may have played an important role in determining survival.
-
Eur J Vasc Endovasc Surg · Nov 1995
The potential of simple clinical information and electrocardiogram to predict mortality of primary elective abdominal aortic reconstruction.
To assess the importance of simple clinical information to predict mortality after primary elective aortic reconstruction. ⋯ The patients' history and clinical examination provides the most useful information for further selection of additional cardiac tests before elective primary aortic reconstruction. The additional value of the electrodiogram is somewhat overestimated.
-
Eur J Vasc Endovasc Surg · Nov 1995
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialDesign issues of a randomised controlled clinical trial on spinal cord stimulation in critical limb ischaemia. ESES Study Group.
Review of the design of a clinical study to evaluate of the efficacy of epidural spinal cord electrical stimulation (ESES) as compared to best medical treatment in patients with nonreconstructible critical limb ischaemia. ⋯ Considering the high incidence of death and amputation, 18 months of follow-up seems adequate to detect a clinically relevant outcome improvement from ESES-treatment, if present. We hope to present the results of this study at the end of 1995.