Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
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Randomized Controlled Trial
Kashin-Beck disease in Sichuan, China: report of a pilot open therapeutic trial.
The objective of the study was to identify adults with symptomatic Kashin-Beck disease (KBD) and observe the efficacy and safety of diclofenac sodium, naproxen, and glucosamine hydrochloride in these adult patients in Rang-tang (Sichuan Province), China. ⋯ This report documents characteristic findings in these patients. Diclofenac sodium, naproxen, and glucosamine hydrochloride produced substantial improvements over baseline in pain relief, physical function, and daily self-care activities in these open observations of adult patients with KBD.
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Randomized Controlled Trial
A randomized controlled trial evaluating the cost-effectiveness of sonographic guidance for intra-articular injection of the osteoarthritic knee.
The present randomized controlled study investigated whether sonographic needle guidance affected the outcomes of intra-articular injection for osteoarthritis of the knee. ⋯ Sonographic needle guidance reduced procedural pain and improved the clinical outcomes and cost-effectiveness of intra-articular injections of the osteoarthritic knee.
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Many clinicians are familiar with the common presentation of Raynaud phenomenon affecting the hands and feet. Patients with Raynaud phenomenon, even in the absence of systemic disease, are frequently treated by rheumatologists. Raynaud phenomenon of the nipple is an important entity to recognize as a cause of severe nipple pain with breast-feeding and is perhaps underrecognized by patients and physicians. We describe a patient with Raynaud phenomenon of the nipple to improve identification of this clinical entity so that appropriate treatment may be instituted, thus allowing mothers to continue nursing.
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It has been suggested that low physical fitness is a contributor to pain in fibromyalgia and that exercise-related beliefs play a role in the persistence of this association. Yet the association between physical fitness and pain is hardly explored in detail. ⋯ The results demonstrate some associations between physical fitness and pain in fibromyalgia and point to the importance of activity avoidance. Although the causal directionality of the associations needs substantiation in clinical research, the findings support the notion that low fitness and activity-avoidance beliefs should be targeted while treating pain in fibromyalgia.