Annals of internal medicine
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Randomized Controlled Trial Clinical Trial
Efficacy of psyllium in reducing serum cholesterol levels in hypercholesterolemic patients on high- or low-fat diets.
To determine the efficacy of psyllium in reducing serum cholesterol levels in patients on high- or low-fat diets. ⋯ Psyllium produces a modest but significant improvement in total cholesterol and LDL cholesterol levels in persons on either low-fat or high-fat diets. Psyllium, when added to a prescribed low-fat diet, may obviate the need for typical lipid-lowering medications or may prove to be a valuable adjunct to other treatments in patients with moderately elevated LDL cholesterol levels.