Annals of internal medicine
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Practice Guideline Guideline
Consensus recommendations for managing patients with nonvariceal upper gastrointestinal bleeding.
The management of patients with acute nonvariceal upper gastrointestinal bleeding has evolved substantially over the past 10 years amid a paucity of published consensus guidelines. ⋯ The efficacy of newer endoscopic therapeutic technologies, the optimal regimen of proton-pump inhibition, and the roles of other pharmacologic agents require further research.
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The incidence of hepatocellular carcinoma was reported to be increasing in the United States. However, alternate explanations were diagnostic or reclassification bias and changes in the demographic features of the general population. ⋯ The incidence of hepatocellular carcinoma continues to increase rapidly in the United States, with rates increasing the fastest in white men 45 to 54 years of age. These findings are consistent with a true increase and could be explained by consequences of hepatitis C virus acquired during the 1960s and 1970s.
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Editorial Comment
Patent cardiac foramen ovale: stroke risk and closure.
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Outcomes and prognostic factors in 267 patients with severe acute respiratory syndrome in Hong Kong.
Severe acute respiratory syndrome (SARS) has become a global public health emergency. ⋯ Because of the longer follow-up period in our cohort, the mortality rate in these patients is higher than rates reported in previous studies. Advanced age and high lactate dehydrogenase level at presentation predict mortality. *For members of the Princess Margaret Hospital SARS Study Group, see the Appendix.